Symptoms
Macular holes develop in stages, and symptoms worsen as the hole progresses:
Early Stage (Foveal Detachment):
- Slightly blurred or distorted central vision
- Straight lines appear wavy (metamorphopsia)
Intermediate Stage (Partial Thickness Hole):
- Central vision distortion increases
- Difficulty reading small print
Advanced Stage (Full-Thickness Hole):
- A dark or blind spot in central vision .
- Peripheral (side) vision remains unaffected.
Note: A macular hole usually affects one eye at a time, though the other eye may also develop one later.
Risk factors
A macular hole typically develops due to age-related changes in the vitreous, the gel-like substance that fills the eye. However, other factors can also contribute. The main causes include:
- Age-Related Vitreous Changes (Idiopathic Macular Hole) – As people age, the vitreous gel slowly shrinks and pulls away from the retina (a process called posterior vitreous detachment or PVD). In some cases, this pulling force (traction) is too strong and can tear the macula, forming a hole.
- High Myopia (Nearsightedness) – People with extreme nearsightedness have a thinner retina, making them more prone to developing macular holes.
- Trauma or Eye Injury – A direct impact to the eye, such as from a sports injury or car accident, can lead to a macular hole.
- Diabetic Eye Disease or Other Retinal Conditions – Conditions like diabetic retinopathy, macular edema, or epiretinal membrane (macular pucker) can increase the risk.
- Retinal Detachment – Sometimes, macular holes occur in conjunction with retinal detachment, a sight-threatening condition.
- Risk to the Other Eye – About 10-15% of patients may develop a macular hole in the second eye.

