Keratoconus

Keratoconus is a degenerative disease of the cornea

Keratoconus is a progressive thinning and bulging of the cornea, in which it gradually takes on a cone-like shape instead of a smooth, spherical surface.
This leads to blurred and distorted vision, increased sensitivity to light, and frequent changes in prescription.

The condition is usually bilateral and asymmetrical, often affecting one eye first and the other years later.

Early diagnosis is crucial, because timely treatment can stop or slow the progression of the disease.

Symptoms

  • Blurred vision, changes in visual acuity, sensitivity to light, and changes in refraction (e.g., needing new glasses every few months).
  • The onset of the disease is usually in adolescence. At this stage, there are often no typical complaints related to vision reduction. Diagnosis in the initial form can only be made during an examination with specialized digital equipment and specific research methods.
  • As the disease progresses, symptoms such as reduced vision, discomfort, and the appearance of astigmatism that is difficult to correct emerge.
  • In more advanced stages, even with glasses, it is impossible to provide sufficiently good vision, and special contact lenses become necessary.
  • In the final stages of the disease, vision correction with glasses and contact lenses is impossible. The thinning of the cornea is highly advanced, and there is central opacity. This necessitates more radical measures, namely surgical treatment – corneal transplantation (keratoplasty).

Risk Factors

The causes of keratoconus are unknown, but it is believed to have a hereditary component – related to a defect in the formation of an important structural protein in the cornea (collagen).

  • Ocular allergies
  • Excessive eye rubbing
  • Genetic diseases – Down syndrome, Ehlers-Danlos syndrome, and Marfan syndrome

Diagnosis

Often, in the initial phase, patients’ complaints may be attributed to another problem; therefore, the doctor’s experience and precise diagnostics are crucial for timely diagnosis.

Beyond the standard examination with a biomicroscope, it is important to perform keratometry (measuring corneal curvature), pachymetry (measuring corneal thickness), and a 3D map of the cornea (corneal topography). Vision Clinic is equipped with the latest equipment for these tests. The clinic is one of the few in Bulgaria that has the latest innovation from the German company “SCHWIND” – “Sirius.” As both a topographer and a tomographer, the device performs a 3D analysis of the cornea and the anterior eye segment in seconds. This non-contact examination detects even the smallest deviations in the corneal surface, which is extremely valuable for the early diagnosis of keratoconus. “Sirius” is also used to calculate contact lenses for patients with this diagnosis.

VISION also has another device – a gold standard for lens fitting – the “E300” corneal topographer from “Medmont.” It performs extremely precise measurements – its standard deviation for error is only 2 microns. For comparison, the average human hair is 75 microns thick.

Treatment

In the initial stages of the disease, vision correction with glasses or contact lenses is undertaken, but as the process progresses, a surgical procedure called Cross-linking is introduced. In the final stage of the disease, perforating keratoplasty (corneal transplantation) may be necessary.
Cross-linking is a procedure that strengthens and reinforces the cornea. The operation uses a combination of riboflavin (Vitamin B2) and special dosed UV light (harmless to the eye structures). Cross-linking strengthens the corneal structure and halts the development and progression of keratoconus. VISION Clinic has the latest, fastest-acting, special UV system “Avedro KXL” for cross-linking, which allows for more precise, safe, and faster execution of the procedure.

Contact Lenses
Soft contact lenses for vision correction in keratoconus and high astigmatism “Kerasoft IC”: With their advent, “Kerasoft IC” soft contact lenses quickly proved their advantages over rigid lenses and led to a change in the treatment approach and improvement of vision in keratoconus. Their advantages include comfortable all-day wear, exceptionally clear vision, increased oxygen permeability necessary for the cornea, and easy maintenance.

The Gold Standard “Rose K2”
Rigid innovative gas-permeable (RGP) lenses “Rose K2” are the gold standard for keratoconus correction in over 90 countries. Invented by New Zealand optometrist Paul Rose, they are made from a special material that allows the cornea to “breathe.” They are custom-made for each patient and come in 6 different designs. Each “Rose K2” type is suitable for a specific type and stage of keratoconus.
The lenses are fitted individually, after which there is a trial wearing period, during which the patient’s subjective sensations and objective clinical signs are monitored during the adaptation period.
“Vision” Clinic is the only one in Bulgaria that offers “Rose K2” lenses.

Mini-Scleral “Rose K2” XL
The mini-scleral “Rose K2” XL is ideal for patients who cannot be fitted with standard rigid lenses.

Piggy-back – “2 in 1” alternative
The “piggy-back” system was developed for patients who have intolerance to gas-permeable (rigid) lenses. For example, it allows a soft contact lens to be placed under the rigid lens, acting as a “cushion.” At the same time, the gas-permeable lens provides clear vision.

Keratoplasty (Corneal Transplantation)
Corneal transplantation has a long history and is among the first and most successful transplantations in medicine. In this type of eye surgery, the diseased corneal tissue is removed and replaced with a healthy donor cornea. The success rate is very high – this is due to the lack of blood vessels in the cornea, which leads to a significantly lower risk of graft rejection reaction.

Perforating Keratoplasty is a method for surgical treatment of preventable corneal blindness with extremely rapid recovery. Advanced keratoconus and corneal dystrophies are among the most common indications for corneal transplantation in Bulgaria.

Prevention

Keratoconus usually cannot be prevented, but one can reduce the risk of its onset.

  • Do not rub or injure your eyes.
  • Protect your eyes from direct sunlight and UV light.
  • Treat your allergies.

Frequently Asked Questions

If not diagnosed and treated in time, keratoconus can progress and cause serious vision problems, including blindness.

The onset of the disease is usually in adolescence. In this stage, there are often no typical complaints related to reduced vision. Diagnosis in the initial form can only be made during an examination with specialized equipment. As the disease progresses, symptoms such as reduced vision, discomfort, and the appearance of astigmatism that is difficult to correct emerge.

Laser vision correction is not applied to patients with keratoconus.

Equipment

Sirius - Topographer
Sirius – Topographer

A modern method for examining the corneal surface

Sirius - Topographer
Avedro KXL® – Cross-linking System
Avedro KXL® – Cross-linking System

The only proven, non-surgical method for treating keratoconus

Avedro KXL® – Cross-linking System
Medmont Meridia™- Topographer
Medmont Meridia™- Topographer

This device is considered the gold standard in precision contact lens fitting

Medmont Meridia™- Topographer